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Malic acid, an organic dicarboxylic acid with two stereoisomeric forms, plays an important biochemical role in both the Calvin cycle and the citric acid cycle. It is used as a food additive and preservative, a therapeutic agent, and a dietary supplement.
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Malic enzyme inhibitor ME1 is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM. It significantly reduces total cell numbers and cell viability/metabolic activity in MTS cells and dose-dependently reduces the number of colonies formed by HCT116 and HT29 cells. This product is for research use only.
Potent inhibitor of malic enzyme (ME1) with an IC50 of 0.15 μM
Reduces total cell numbers and cell viability in MTS cells
Dose-dependently reduces colony formation in HCT116 and HT29 cells
Appears as a white to off-white solid
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The racemate of L-malic acid; reduces IFN-γ and TNF-α-induced CCL2 and ICAM expression in HaCaT human keratinocytes at 1 mM; inhibits epidermis and dermis thickening, as well as mast cell and eosinophil dermal infiltration in a mouse model of DNBC-induced atopic dermatitis at 10 mM
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D-(+)-Malic acid, also known as D-Malic acid, is an active enantiomer of Malic acid. It serves as a competitive inhibitor of L-(-)malic acid transport. This product is an analytical standard of D-(+)-Malic acid, specifically intended for research and analytical applications.
Competitive inhibitor of L-(-)malic acid transport
Suitable for research and analytical applications
Enantiomer of Malic acid
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Malic acid-d3 is the deuterium labeled Malic acid Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears It plays a role in many sour or tart foods[1][2]
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Malic enzyme inhibitor ME1 is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM. It is intended for research use only and has been shown to significantly impact cell viability and proliferation in various cell lines.
Potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM
Significantly reduces total cell numbers and cell viability/metabolic activity in MTS cells
Dose-dependently reduces the number of colonies formed by HCT116 and HT29 cells
Suitable for research applications
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More