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Malic acid, an organic dicarboxylic acid with two stereoisomeric forms, plays an important biochemical role in both the Calvin cycle and the citric acid cycle. It is used as a food additive and preservative, a therapeutic agent, and a dietary supplement.
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(S)-Malic acid (Standard) is the analytical standard of (S)-Malic acid This product is intended for research and analytical applications (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form contributes to the pleasantly sour taste of fruits and is used as a food additive In Vitro It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L casei Furthermore deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S)-2-Hydroxysuccinic acid thus indicating that the cognate TC system regulates and is essential for the expression of ME Transcriptional analyses shows that expression of maeE is induced in the presence of (S)-2-Hydroxysuccinic acid and repressed by glucose whereas TC system expression is induced by (S)-2-Hydroxysuccinic acid and is not repressed by glucose[1]
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Malic acid disodium salt is the disodium salt of malic acid (sodium DL-malate) supplied as a high-purity biochemical reagent. It is commonly used as a buffering agent, pH regulator, and reagent in biochemical assays and food additive research.
High purity (98.0%) for reliable experimental results.
Useful as a buffering agent in aqueous solutions.
Suitable for biochemical assay and buffer preparation.
White crystalline powder, easy to weigh and handle.
Molecular formula C4H4Na2O5; molecular weight 178.05.
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Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities Malic acid plays a role in many sour or tangy foods Malic acid is an intermediate in the citric acid cycle[1][2]
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Malic enzyme inhibitor ME1 is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM. It is intended for research use only and has been shown to significantly impact cell viability and proliferation in various cell lines.
Potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM
Significantly reduces total cell numbers and cell viability/metabolic activity in MTS cells
Dose-dependently reduces the number of colonies formed by HCT116 and HT29 cells
Suitable for research applications
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D-(+)-Malic acid, also known as D-Malic acid, is an active enantiomer of Malic acid. It serves as a competitive inhibitor of L-(-)malic acid transport. This product is an analytical standard of D-(+)-Malic acid, specifically intended for research and analytical applications.
Competitive inhibitor of L-(-)malic acid transport
Suitable for research and analytical applications
Enantiomer of Malic acid
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D-(+)-Malic acid is the analytical standard for D-(+)-Malic acid, intended for research and analytical applications. It is an active enantiomer of Malic acid and a competitive inhibitor of L-(-)-malic acid transport.
The compound is an analytical standard, used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Appearance: solid
Color: white to off-white
Initial source: plants Rosaceae Malus pumila Mill. and microorganisms
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(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form contributes to the pleasantly sour taste of fruits and is used as a food additive
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D-(+)-Malic acid (D-Malic acid) is an active enantiomer of Malic acid that functions as a competitive inhibitor of L(-)malic acid transport. It is an endogenous metabolite.
Active enantiomer of malic acid
Competitive inhibitor of L(-)malic acid transport
Can be produced from maleic acid by certain bacteria
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